USP L114 column: Zwitterionic sulfobetaine on silica

Zwitterionic sulfobetaine groups grafted onto porous silica of 1.5-10 um, or onto a monolithic rod.

Mode: HILIC   Typical pH range: about 2-8 (silica base)

Typical uses

  • Very polar drugs, counter-ions and metabolites by HILIC
  • Polar impurities not retained on C18

Common sizes (length x internal diameter, particle size)

  • 150 x 4.6 mm, 5 um
  • 100 x 2.1 mm, 1.7-3.5 um

Tender wording (brand-neutral)

HPLC column with USP L114 packing (Zwitterionic sulfobetaine on silica), 150 x 4.6 mm, 5 um (length x internal diameter, particle size); stainless-steel or equivalent hardware with standard fittings; recommended pH and temperature range to be stated by the bidder; each column supplied with its certificate of analysis and test chromatogram, batch/lot number and serial number; shelf life not less than 2 years from delivery; any make meeting the USP L114 designation and the stated dimensions is acceptable.

Size:

Changing length or particle size

You can keep the USP L114 packing and use a different length, particle size or diameter within the harmonized USP 621 limits. Check your columns with the calculator.

Related column types

L82 Polyamine on polyvinyl alcohol

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