USP L24 column: Polyvinyl alcohol on silica
Polyvinyl alcohol bonded to porous silica particles of about 5 um (older editions described a hydrophilic vinyl polymer gel of larger size).
Mode: other Typical pH range: about 2-8 (silica base)
Typical uses
- Hydrophilic / normal-phase type separations
- Few monograph methods
Common sizes (length x internal diameter, particle size)
- 250 x 4.6 mm, 5 um
- 150 x 4.6 mm, 5 um
Description has changed between USP editions; confirm against the current USP-NF.
Tender wording (brand-neutral)
HPLC column with USP L24 packing (Polyvinyl alcohol on silica), 250 x 4.6 mm, 5 um (length x internal diameter, particle size); stainless-steel or equivalent hardware with standard fittings; recommended pH and temperature range to be stated by the bidder; each column supplied with its certificate of analysis and test chromatogram, batch/lot number and serial number; shelf life not less than 2 years from delivery; any make meeting the USP L24 designation and the stated dimensions is acceptable.
Size:
Changing length or particle size
You can keep the USP L24 packing and use a different length, particle size or diameter within the harmonized USP 621 limits. Check your columns with the calculator.
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