Apreon

What Apreon (Aprepitant) is used for

Aprepitant is an anti-sickness (antiemetic) medicine. It belongs to a group called NK1 receptor antagonists: it blocks a natural brain chemical (neurokinin) that sets off nausea and vomiting. It is used to prevent sickness caused by cancer chemotherapy, always together with other anti-sickness medicines. It comes as capsules, as a liquid (oral suspension) for children, and as an injection into a vein. It is prescribed by the cancer care team, and WHO includes it on its Essential Medicines List for people having chemotherapy that is strongly or moderately likely to cause sickness.

• Preventing nausea and vomiting caused by chemotherapy that is strongly or moderately likely to make people sick, such as treatment with cisplatin, cyclophosphamide, doxorubicin or epirubicin
• Preventing delayed sickness that can start some days after certain chemotherapy
• It is used together with other anti-sickness medicines, usually a steroid (dexamethasone) and a medicine such as ondansetron
• Children: the liquid is used in younger children and the capsules in teenagers, under the cancer team
• In some countries, such as the US, it is also approved to prevent sickness after surgery

Side effects, warnings and interactions for Aprepitant

Prepared from the sources listed by the MedInfoBase team. General information, not medical advice: it gives no doses. Your doctor or pharmacist decides the medicine and dose for you.