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Product details
- Generic
- Methotrexate
- Therapeutic area
- Oncology & immunology
- Drug class
- Antimetabolite / immunomodulator
- ATC
- L01BA
- Strength
- 50 mg (25 mg/mL)
- Dosage form
- Injection
- Pack
- 1's
- Registration no.
- 047541
- Price record verified
- 2026-08-07
- Latest DRAP source check
- 2026-11-12 02:58
Manufacturer
Atco Pharma International (Pvt) Ltd
Explore this manufacturer's complete MedInfoBase portfolio, generics and current listed prices.
View company portfolio →What Zexate (Methotrexate) is used for
Methotrexate is a prescription medicine that calms down the immune system and eases inflammation. It belongs to a group of medicines that affect how cells grow (antimetabolites). It comes as tablets, a liquid, or injections. It is started and supervised by specialists, and people on it need regular check-ups and blood tests. It is a powerful medicine: following your prescriber's exact schedule is vital, because taking it the wrong way by mistake can be fatal.
- Inflammatory conditions such as rheumatoid arthritis, psoriasis (including psoriatic arthritis) and Crohn's disease
- Severe psoriasis and rheumatoid arthritis, usually when other treatments have not helped
- Arthritis and some other inflammatory conditions in children, under a children's rheumatology team
- Some types of cancer, usually given as an injection in hospital
- Other conditions a specialist may choose to treat, such as multiple sclerosis
Get medical help straight away if
- Call an ambulance for signs of a severe allergic reaction: swelling of the lips, mouth, tongue or throat, very fast breathing, wheezing or struggling to breathe, a tight throat, blue, grey or pale skin or lips, or sudden confusion or fainting.
- Seek emergency care for seizures, confusion, loss of consciousness, sudden blurred vision or loss of sight, or weakness or difficulty moving one or both sides of the body.
- Contact a doctor or call 111 straight away for signs of infection: fever, chills, sore throat, muscle aches or mouth ulcers.
- Get help straight away for unusual bruising or bleeding, bleeding gums, blood in the urine, black or bloody stools, or being sick with blood.
Side effects, warnings and interactions for Methotrexate
Prepared from the sources listed by the MedInfoBase team. General information, not medical advice: it gives no doses. Your doctor or pharmacist decides the medicine and dose for you.
Our condition guides that mention Methotrexate
From our condition guides, written from WHO, NICE and other opened sources. Your doctor decides if Methotrexate is right for you and the dose.
- Eczema (atopic dermatitis): for severe eczema that has not responded to creams, prescribed and monitored by a skin specialist
- Psoriasis: For extensive, severe or very distressing psoriasis when creams and light treatment are not enough
- Rheumatoid arthritis: main long-term treatment started early to slow joint damage
About Zexate 50 mg (25 mg/mL) injection
Zexate 50 mg (25 mg/mL) injection contains Methotrexate 50 mg (25 mg/mL). It is registered with DRAP by Atco Pharma International (Pvt) Ltd (registration no. 047541). Its official price is PKR 360.08 for a pack of 1's. This price has applied since 22 July 2026. Zexate is also available as 25 mg/mL (50 mg total) injection. No other brand of Methotrexate 50 mg (25 mg/mL) in this form is listed in Pakistan.
Other strengths of Zexate
Other brands of Methotrexate 50 mg (25 mg/mL) injection in Pakistan
No other brand of Methotrexate 50 mg (25 mg/mL) injection is listed in Pakistan. See all strengths and forms of Methotrexate →
Where to buy
MedInfoBase does not sell medicines and takes no orders. The company below holds the DRAP registration for Zexate, so it is the right place for a pharmacy, distributor or hospital buyer to ask about supply. A patient should buy from a licensed pharmacy.
- Registration holder
- Atco Pharma International (Pvt) Ltd, Karachi
- DRAP registration
- 047541
- Phone
- +92 21 111111645
Contact details as published by the company, last checked on 16 August 2026 (not yet independently verified). The price on this page is the official DRAP maximum retail price: a pharmacy may charge that or less, never more.
Official price over time
No change in the official DRAP price is recorded for this pack (1's). Current price PKR 360.08, effective 22 Jul 2026.
Cite this price history
MedInfoBase. Zexate 50 mg (25 mg/mL), 1's: official price history (source: DRAP PharmaPrice Index). https://medinfobase.com/brand/zexate-50-mg-25-mg-ml-047541-1s-atco-pharma-international-pvt-ltd/ (accessed 12 November 2026).
Official price history
| Amount | Effective from | Verified | Source | Status |
|---|---|---|---|---|
| PKR 360.08 | 2026-07-22 | 2026-08-07 | DRAP PharmaPrice Index | Current |
Cite this record
Medicine record · DRAP registration 047541Price and registration data on this page were observed on 7 August 2026. Records change over time, so please cite the observation date alongside the access date.