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Product details
- Generic
- Sulfadoxine + Pyrimethamine
- Therapeutic area
- Anti-infectives
- Drug class
- Antimalarials
- ATC
- P01BD
- Strength
- 500 mg + 25 mg
- Dosage form
- Tablet
- Pack
- 1's
- Registration no.
- 018773
- Price record verified
- 2026-08-24
- Latest DRAP source check
- 2026-11-12 02:58
Manufacturer
Zephyr Pharmatec (pvt) limited
Explore this manufacturer's complete MedInfoBase portfolio, generics and current listed prices.
View company portfolio →What Irene (Sulfadoxine-pyrimethamine) is used for
Sulfadoxine-pyrimethamine (often shortened to SP) is an antimalarial medicine that combines two drugs. Sulfadoxine is a sulfonamide ("sulfa") drug. It is used in public-health programmes to protect people from malaria, rather than as a medicine for everyday illness. It is given by health workers or on a clinic's advice, and the clinic decides when it is started.
- Preventing malaria in pregnancy. This is called intermittent preventive treatment in pregnancy (IPTp). WHO recommends it in parts of Africa where malaria spreads at moderate to high levels.
- Preventing malaria in babies, in some programmes (the WHO-prequalified leaflet covers babies in their first year)
- Seasonal malaria chemoprevention: given together with another antimalarial (amodiaquine) to young children in areas where malaria spreads mainly in one season, such as parts of the Sahel
- Treating malaria in some settings, mostly in the past (WHO describes SP as used for decades in malaria treatment)
Get medical help straight away if
- Stop the medicine and get medical help at once for any skin rash or itching, because a rash can be the first sign of a serious skin reaction.
- Get urgent help for severe skin reactions such as Stevens-Johnson syndrome (blistering or peeling skin, sores in the mouth or eyes).
- Get urgent help for signs of a serious allergic reaction, such as swelling of the face, lips or throat, or trouble breathing.
- Get urgent help for yellow skin or eyes, or other signs of liver damage. Liver toxicity is rare but serious.
Side effects, warnings and interactions for Sulfadoxine-pyrimethamine
Prepared from the sources listed by the MedInfoBase team. General information, not medical advice: it gives no doses. Your doctor or pharmacist decides the medicine and dose for you.
About Irene 500 mg + 25 mg tablet
Irene 500 mg + 25 mg tablet contains Sulfadoxine + Pyrimethamine 500 mg + 25 mg. It is registered with DRAP by Zephyr Pharmatec (pvt) limited (registration no. 018773). Its official price is PKR 6.93 for a pack of 1's. The price changed from PKR 6.61 to PKR 6.93 on 17 August 2026. It is sold in 3 pack sizes: 1's, 2's and 10's. 14 other brands of Sulfadoxine + Pyrimethamine 500 mg + 25 mg (tablet) are registered in Pakistan. Compare all brands and prices →
Irene 500 mg + 25 mg pack sizes and prices
All 14 other brands of Sulfadoxine + Pyrimethamine 500 mg + 25 mg tablet in Pakistan
These 14 brands are alternatives (substitutes) to Irene: each contains Sulfadoxine + Pyrimethamine 500 mg + 25 mg tablet. Ask your doctor or pharmacist before you switch brands.
Sorted by price per tablet, lowest first. The lowest is Sinofen (Saffron Pharmaceuticals) at PKR 6.23 per tablet; the highest is MALAREST at PKR 27.32. All prices are official DRAP prices.
| Brand | Company | Pack | Official price | Per unit |
|---|---|---|---|---|
| Sinofen | Saffron Pharmaceuticals | 10’s | PKR 62.33 | PKR 6.23 / tablet |
| Melofin | Shaigan Pharmaceuticals (Pvt) Ltd | 3's | PKR 19.19 | PKR 6.40 / tablet |
| FANSIWIL | Wilshire Laboratories (Private) Limited | 10's | PKR 65.23 | PKR 6.52 / tablet |
| Mosquit | Pharmatec Pakistan (Pvt.) Limited | 100's | PKR 711.91 | PKR 7.12 / tablet |
| Maladrin | Bosch Pharmaceuticals (Pvt) Ltd | 2's | PKR 15.53 | PKR 7.77 / tablet |
| Falcicure | S.J & G. Fazul Ellahie (pvt) limited | 2's | PKR 16.19 | PKR 8.10 / tablet |
| Fensid | Mediate Pharmaceutical Pvt Ltd | 1X10'S | PKR 108.83 | PKR 10.88 / tablet |
| FANSIDAR | Martin Dow Limited | 10's | PKR 123.91 | PKR 12.39 / tablet |
| Eudar | UNEXOLABS (PVT) LTD | 10's | PKR 262.23 | PKR 26.22 / tablet |
| Hamadar | Hamaz Pharmaceuticals (Pvt) Ltd | 10's | PKR 262.27 | PKR 26.23 / tablet |
| Maladar | Efroze Chemical Industries Pvt. Ltd | 3's | PKR 81.95 | PKR 27.32 / tablet |
| MALAREST | Pharmedic Laboratories (Pvt.) Ltd Lahore | 10’s | PKR 273.20 | PKR 27.32 / tablet |
| ARGENT 100 | Hilton Pharma (Pvt) Limited | 9's combo | PKR 204.14 | — |
| ARGENT 50 | Hilton Pharma (Pvt) Limited | 8's combo | PKR 116.65 | — |
See every strength and form of Sulfadoxine + Pyrimethamine →
Where to buy
MedInfoBase does not sell medicines and takes no orders. The company below holds the DRAP registration for Irene, so it is the right place for a pharmacy, distributor or hospital buyer to ask about supply. A patient should buy from a licensed pharmacy.
- Registration holder
- Zephyr Pharmatec (pvt) limited, Karachi
- DRAP registration
- 018773
- Website
- http://www.zephyrpharmatec.com/
Contact details as published by the company, last checked on 16 August 2026 (not yet independently verified). The price on this page is the official DRAP maximum retail price: a pharmacy may charge that or less, never more.
Official price over time
PKR 6.61 to 6.93 (+4.8%) between 5 Sep 2025 and 17 Aug 2026 · 2 official price records · pack 1's
Step chart: a notified price holds until DRAP notifies the next one. Hover or tap a point for its date and change.
Cite this price history
MedInfoBase. Irene 500 mg + 25 mg, 1's: official price history (source: DRAP PharmaPrice Index). https://medinfobase.com/brand/irene-500-mg-25-mg-018773-1s-zephyr-pharmatec-pvt-limited-1326/ (accessed 12 November 2026).
Official price history
| Amount | Effective from | Verified | Source | Status |
|---|---|---|---|---|
| PKR 6.93 | 2026-08-17 | 2026-08-24 | DRAP PharmaPrice Index | Current |
| PKR 6.61 | 2025-09-05 | 2026-08-07 | DRAP PharmaPrice Index | Historical |
Cite this record
Medicine record · DRAP registration 018773Price and registration data on this page were observed on 24 August 2026. Records change over time, so please cite the observation date alongside the access date.