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Product details
- Generic
- Sulfadoxine + Pyrimethamine
- Therapeutic area
- Anti-infectives
- Drug class
- Antimalarials
- ATC
- P01BD
- Strength
- 500 mg + 25 mg
- Dosage form
- Tablet
- Pack
- 3's
- Registration no.
- 025945
- Price record verified
- 2026-08-09
- Latest DRAP source check
- 2026-11-13 03:02
Manufacturer
Shaigan Pharmaceuticals (Pvt) Ltd
Explore this manufacturer's complete MedInfoBase portfolio, generics and current listed prices.
View company portfolio →What Melofin (Sulfadoxine-pyrimethamine) is used for
Sulfadoxine-pyrimethamine (often shortened to SP) is an antimalarial medicine that combines two drugs. Sulfadoxine is a sulfonamide ("sulfa") drug. It is used in public-health programmes to protect people from malaria, rather than as a medicine for everyday illness. It is given by health workers or on a clinic's advice, and the clinic decides when it is started.
- Preventing malaria in pregnancy. This is called intermittent preventive treatment in pregnancy (IPTp). WHO recommends it in parts of Africa where malaria spreads at moderate to high levels.
- Preventing malaria in babies, in some programmes (the WHO-prequalified leaflet covers babies in their first year)
- Seasonal malaria chemoprevention: given together with another antimalarial (amodiaquine) to young children in areas where malaria spreads mainly in one season, such as parts of the Sahel
- Treating malaria in some settings, mostly in the past (WHO describes SP as used for decades in malaria treatment)
Get medical help straight away if
- Stop the medicine and get medical help at once for any skin rash or itching, because a rash can be the first sign of a serious skin reaction.
- Get urgent help for severe skin reactions such as Stevens-Johnson syndrome (blistering or peeling skin, sores in the mouth or eyes).
- Get urgent help for signs of a serious allergic reaction, such as swelling of the face, lips or throat, or trouble breathing.
- Get urgent help for yellow skin or eyes, or other signs of liver damage. Liver toxicity is rare but serious.
Side effects, warnings and interactions for Sulfadoxine-pyrimethamine
Prepared from the sources listed by the MedInfoBase team. General information, not medical advice: it gives no doses. Your doctor or pharmacist decides the medicine and dose for you.
About Melofin 500 mg + 25 mg tablet
Melofin 500 mg + 25 mg tablet contains Sulfadoxine + Pyrimethamine 500 mg + 25 mg. It is registered with DRAP by Shaigan Pharmaceuticals (Pvt) Ltd (registration no. 025945). Its official price is PKR 19.19 for a pack of 3's, about PKR 6.40 per tablet. The price changed from PKR 18.29 to PKR 19.19 on 18 August 2026. It is sold in 2 pack sizes: 3's and 10's. 14 other brands of Sulfadoxine + Pyrimethamine 500 mg + 25 mg (tablet) are registered in Pakistan. Compare all brands and prices →
Melofin 500 mg + 25 mg pack sizes and prices
| Pack | Official price | Per tablet |
|---|---|---|
| 3's (this page) | PKR 19.19 | PKR 6.40 |
| 10's | PKR 81.04 | PKR 8.10 |
All 14 other brands of Sulfadoxine + Pyrimethamine 500 mg + 25 mg tablet in Pakistan
These 14 brands are alternatives (substitutes) to Melofin: each contains Sulfadoxine + Pyrimethamine 500 mg + 25 mg tablet. Ask your doctor or pharmacist before you switch brands.
Sorted by price per tablet, lowest first. The lowest is Sinofen (Saffron Pharmaceuticals) at PKR 6.23 per tablet; the highest is MALAREST at PKR 27.32. All prices are official DRAP prices.
| Brand | Company | Pack | Official price | Per unit |
|---|---|---|---|---|
| Sinofen | Saffron Pharmaceuticals | 10’s | PKR 62.33 | PKR 6.23 / tablet |
| FANSIWIL | Wilshire Laboratories (Private) Limited | 10's | PKR 65.23 | PKR 6.52 / tablet |
| Irene | Zephyr Pharmatec (pvt) limited | 1's | PKR 6.93 | PKR 6.93 / tablet |
| Mosquit | Pharmatec Pakistan (Pvt.) Limited | 100's | PKR 711.91 | PKR 7.12 / tablet |
| Maladrin | Bosch Pharmaceuticals (Pvt) Ltd | 2's | PKR 15.53 | PKR 7.77 / tablet |
| Falcicure | S.J & G. Fazul Ellahie (pvt) limited | 2's | PKR 16.19 | PKR 8.10 / tablet |
| Fensid | Mediate Pharmaceutical Pvt Ltd | 1X10'S | PKR 108.83 | PKR 10.88 / tablet |
| FANSIDAR | Martin Dow Limited | 10's | PKR 123.91 | PKR 12.39 / tablet |
| Eudar | UNEXOLABS (PVT) LTD | 10's | PKR 262.23 | PKR 26.22 / tablet |
| Hamadar | Hamaz Pharmaceuticals (Pvt) Ltd | 10's | PKR 262.27 | PKR 26.23 / tablet |
| Maladar | Efroze Chemical Industries Pvt. Ltd | 3's | PKR 81.95 | PKR 27.32 / tablet |
| MALAREST | Pharmedic Laboratories (Pvt.) Ltd Lahore | 10’s | PKR 273.20 | PKR 27.32 / tablet |
| ARGENT 100 | Hilton Pharma (Pvt) Limited | 9's combo | PKR 204.14 | — |
| ARGENT 50 | Hilton Pharma (Pvt) Limited | 8's combo | PKR 116.65 | — |
See every strength and form of Sulfadoxine + Pyrimethamine →
Where to buy
MedInfoBase does not sell medicines and takes no orders. The company below holds the DRAP registration for Melofin, so it is the right place for a pharmacy, distributor or hospital buyer to ask about supply. A patient should buy from a licensed pharmacy.
- Registration holder
- Shaigan Pharmaceuticals (Pvt) Ltd, Rawalpindi
- DRAP registration
- 025945
- Phone
- +92 51 5133060-8
- info@shaigan.com
- Website
- https://shaigan.com/
- Contact page
- Company contact page
Contact details as published by the company, last checked on 16 August 2026 (not yet independently verified). The price on this page is the official DRAP maximum retail price: a pharmacy may charge that or less, never more.
Official price over time
PKR 18.29 to 19.19 (+4.9%) between 24 Sep 2025 and 18 Aug 2026 · 2 official price records · pack 3's
Step chart: a notified price holds until DRAP notifies the next one. Hover or tap a point for its date and change.
Cite this price history
MedInfoBase. Melofin 500 mg + 25 mg, 3's: official price history (source: DRAP PharmaPrice Index). https://medinfobase.com/brand/melofin-500-mg-25-mg-025945-10s-shaigan-pharmaceuticals-pvt-ltd/ (accessed 13 November 2026).
Official price history
| Amount | Effective from | Verified | Source | Status |
|---|---|---|---|---|
| PKR 19.19 | 2026-08-18 | 2026-09-22 | DRAP PharmaPrice Index (refreshed from snapshot #84) | Current |
| PKR 18.29 | 2025-09-24 | 2026-08-09 | DRAP PharmaPrice Index | Historical |
Cite this record
Medicine record · DRAP registration 025945Price and registration data on this page were observed on 22 September 2026. Records change over time, so please cite the observation date alongside the access date.