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Colistimethate sodium brands and prices in Pakistan

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Colistimethate sodium · ATC J01 · Anti-infectives · Polymyxin antibacterials

Data statusRegistration & price fields require source verification.
25brand families
59registered presentations
22companies
59with current prices
Overview

Colistimethate sodium brands in Pakistan

25 brands of Colistimethate sodium are registered in Pakistan, from 22 companies, in 59 presentations (strength, form and pack size). The most common are 1 MIU injection (15 brands), 2 MIU injection (7 brands) and 4.5 MIU injection (6 brands). For Colistimethate sodium 1 MIU injection, the lowest official price is PKR 1,109 per vial (OLMETHATE by SAMI Pharmaceuticals Pvt. Ltd), the middle (median) price is PKR 1,200 per vial and the highest is PKR 3,617 per vial (Mellistin). Prices are the official maximum retail prices in DRAP records. Brands with the same strength and form contain the same medicine; ask your doctor or pharmacist before you switch brands.

Colistimethate sodium price in Pakistan by strength and form

Strength and formBrandsLowest priceMedian priceHighest price
1 MIU injection15PKR 1,109 / vialOLMETHATEPKR 1,200 / vialPKR 3,617 / vialMellistin
2 MIU injection7PKR 1,727 / vialKompletPKR 2,000 / vialPKR 2,000 / vialGenthate
4.5 MIU injection6PKR 3,887 / vialKompletPKR 4,354 / vialPKR 4,502 / vialListono
150 mg injection4PKR 4,502 / vialCholigenePKR 4,502 / vialPKR 4,502 / vialCBA 150
3 MIU injection4PKR 2,881 / vialColistimPKR 3,001 / vialPKR 3,001 / vialNogotex
4.5 MIU (≈150 mg colistin base activity) injection4PKR 3,474 / vialColistizonPKR 4,502 / vialPKR 4,502 / vialNogotex
2 MIU (≈68 mg colistin base activity) injection3PKR 2,000 / vialColemsetPKR 2,000 / vialPKR 3,089 / vialColistizon
1 MIU (≈34 mg colistin base activity) injection2PKR 1,200 / vialColemset—PKR 1,853 / vialColistizon
100 mg injection2PKR 3,001 / vialColicraft—PKR 3,001 / vialBiothate
2 MIU infusion2PKR 2,000 / unitColimethate—PKR 2,000 / unitColistimethate Sodium

6 less common strengths and forms are in the brand list below.

About Colistimethate (colistin) injection

Colistimethate sodium is an antibiotic from the polymyxin group; in the body it works as colistin. It kills certain bacteria. It comes as a powder that is mixed with liquid and given into a vein, usually by doctors and nurses in hospital. It is kept as a last-resort antibiotic for serious infections when other antibiotics will not work or are not suitable, and specialists decide when it is needed.

What it is used for

  • Serious infections caused by certain bacteria, when other antibiotics are not suitable
  • Infections caused by bacteria that resist many other antibiotics, including carbapenem-resistant Enterobacterales (WHO lists it for this)
  • Rarely, it is given into the fluid around the brain or spine for serious infections there
  • As an inhaled form (through a nebuliser), it is also used for long-term chest infections caused by Pseudomonas bacteria in people with cystic fibrosis

What it is not for

  • It does not work for colds, flu or other infections caused by viruses.
  • It is not used for everyday or simple infections. WHO places colistin in its 'Reserve' group of antibiotics, which are kept as a last resort for infections caused by bacteria that resist many other medicines.
  • WHO lists carbapenem-resistant bacteria as critical-priority threats because they resist last-resort antibiotics, and it says misuse and overuse of antibiotics drive resistance. Using colistin only when really needed helps keep it working.
  • Pakistan: a study at two large hospitals in Faisalabad found some E. coli bacteria from urine and pus samples carrying a gene (mcr-1) that makes them resist colistin. All of these germs also resisted many other antibiotics. The authors call for closer monitoring in Pakistan.

Common side effects

  • Upset stomach
  • Rash, hives or itching, sometimes appearing later in treatment
  • Pain or irritation where the drip goes in
  • Dizziness
  • Kidney problems, usually picked up in blood tests
  • With the inhaled form: cough, chest tightness, sore mouth or throat, or thrush

Get medical help straight away if

  • Get emergency help for signs of a severe allergic reaction: rash, swelling of the face, tongue or throat, trouble breathing, or passing out.
  • Get emergency help for shallow, slow or difficult breathing, or muscle weakness. Very rarely, it can weaken the muscles used for breathing.
  • Tell the medical team straight away about numbness or tingling in the face, tongue, arms or legs, a feeling of insects crawling on the skin, slurred speech, confusion, loss of balance or problems with your sight.
  • Tell the medical team straight away if you pass much less urine than usual, which can be a sign of kidney damage.
  • Tell the medical team straight away about muscle spasms, tiredness or passing much more urine than usual.
  • Severe watery or bloody diarrhoea, with or without fever or stomach cramps. This can start during treatment or some time after it ends.

Who should not take it, or should take care

  • It must not be given if you are allergic to colistimethate sodium, colistin or other polymyxin antibiotics.
  • Tell your doctor if you have or have had kidney problems. Your kidneys will be checked with blood tests during treatment.
  • Tell your doctor if you have myasthenia gravis (a muscle-weakness condition), porphyria or asthma.
  • Newborn and premature babies need special care because their kidneys are not fully developed.
  • Pregnancy: it is not known to harm an unborn baby, but it is only given when really needed. Talk to your doctor.
  • Breastfeeding: small amounts pass into breast milk. The Irish medicine leaflet says breastfeeding is not recommended, while the UK leaflet says to watch the baby for signs of illness if you carry on. Ask your doctor.
  • Tell your doctor or dentist that you are having it before any operation.

Medicines and drinks that can interact

  • Aminoglycoside antibiotics: raise the risk of kidney, nerve and hearing side effects
  • Cephalosporin antibiotics: raise the risk of kidney damage
  • Muscle relaxants used during general anaesthesia: their effect may be stronger. Tell your anaesthetist.
  • Macrolide or fluoroquinolone antibiotics in people with myasthenia gravis: higher risk of muscle weakness and breathing problems
  • Having the injected and inhaled forms at the same time may increase side effects
  • Tell your doctor about all medicines, vitamins and herbal products you take.

Always tell your doctor and pharmacist about every medicine, supplement and herbal product you take.

Using it safely

  • It should only be given when a doctor prescribes it. Complete the full course your doctor plans, even if you feel better, so the infection does not come back and bacteria do not become resistant.
  • Your dose is worked out by your doctor for you, based on your weight, your kidneys and how serious the infection is.
  • You will need regular blood tests to check your kidneys and how you are responding.
  • Tell your doctor if you are not getting better after the first few days, or if you feel worse.
  • Some people are taught to have it at home. If you are, follow your care team's instructions exactly.
  • Do not drive or use machines if you feel dizzy or confused or your sight is affected.
  • Never share your medicine. Once mixed, it should normally be used straight away, and any leftover liquid thrown away.

Common questions

Why is colistin called a last-resort antibiotic?
WHO places colistin in its 'Reserve' group: antibiotics kept for serious infections caused by bacteria that resist many other medicines. Doctors use it when other antibiotics will not work, so that it keeps working for the patients who need it most.

Why do I need blood tests while having it?
Colistimethate can affect the kidneys and nerves. Blood tests let your team check your kidneys and adjust your treatment.

Is colistin resistance a problem in Pakistan?
It has been found. A study at two hospitals in Faisalabad found E. coli carrying a colistin-resistance gene (mcr-1), and these germs also resisted many other antibiotics. This is why colistin should only be used when a doctor decides it is really needed.

Is the inhaled form the same medicine?
It is the same medicine but used in a nebuliser, mainly for long-term chest infections in people with cystic fibrosis. Having the inhaled and injected forms together may increase side effects, so make sure your doctors know about both.

Sources (7)
  1. emc (electronic medicines compendium, UK). [brand name removed] 1 million or 2 million International Units (IU), powder for solution for injection, infusion or inhalation (colistimethate sodium) - patient information leaflet [brand name removed] (2024).
  2. HPRA (Health Products Regulatory Authority, Ireland). Colistimethate sodium 1 million IU and 2 million IU Powder for solution for injection/infusion (2023).
  3. MedlinePlus (US National Library of Medicine). Colistimethate Injection: MedlinePlus Drug Information (2016).
  4. WHO. Colistin (injection) - 6.2.3. Reserve group antibiotics (WHO eEML recommendation, print view).
  5. WHO. Colistin (oral) (WHO eEML, print view).
  6. WHO. WHO updates list of drug-resistant bacteria most threatening to human health (2024).
  7. Frontiers in Microbiology (Abdullah S et al.). Dissemination of clinical Escherichia coli harboring the mcr-1 gene in Pakistan (2025).

Prepared from the sources listed by the MedInfoBase team. General information, not medical advice: it gives no doses. Your doctor or pharmacist decides the medicine and dose for you.

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Pakistan brand index

Available brands

One brand is shown once per manufacturer; strengths, forms, packs and DRAP registrations remain visible as separate presentations.
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25 brands · 59 presentations
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BrandManufacturerRegistered presentations
Biothate2 presentations Biogen Pharma
1 MIU IV injection 1’s 117616 PKR 1,199.812026-09-25 PKR 1,199.81/ vial/unit
100 mg Injection 1's 124501 PKR 3,000.772026-08-20 PKR 3,000.77/ vial/unit
CBA 1501 presentation Biocare Pharmaceutica
150 mg Injection 1,s Vial 103783 PKR 4,502.042026-07-23 PKR 4,502.04/ vial/unit
Choligene3 presentations Genetics Pharmaceuticals Pvt. Ltd
150 mg Injection 1s 121517 PKR 4,501.602026-07-27 PKR 4,501.60/ vial/unit
34 mg Injection 1s 121519 PKR 1,199.812026-07-27 PKR 1,199.81/ vial/unit
68 mg Injection 1s 121518 PKR 2,000.072026-07-27 PKR 2,000.07/ vial/unit
Colaite1 presentation English Pharmaceutical Industries
1 MIU IV injection 1's 092529 PKR 1,199.812026-07-27 PKR 1,199.81/ vial/unit
Colemset3 presentations Solaris Life Sciences Private Limited,
1 MIU (≈34 mg colistin base activity) Injection 1's 123688 PKR 1,199.812026-07-23 PKR 1,199.81/ vial/unit
2 MIU (≈68 mg colistin base activity) Injection 1's 123689 PKR 2,000.072026-07-23 PKR 2,000.07/ vial/unit
4.5 MIU Injection 1's 124113 PKR 4,501.602026-07-23 PKR 4,501.60/ vial/unit
Colemset-3MIU1 presentation Solaris Life Sciences Private Limited,
3 MIU (approx. 100 mg colistin base activity) Injection 1's 124112 PKR 3,000.682026-07-23 PKR 3,000.68/ vial/unit
Coliate2 presentations English Pharmaceutical Industries
2 MIU (≈68 mg colistin base activity) Injection 1's 115682 PKR 2,000.072026-07-27 PKR 2,000.07/ vial/unit
4.5 MIU (≈150 mg colistin base activity) Injection 1's 116494 PKR 4,501.602026-07-27 PKR 4,501.60/ vial/unit
Colicraft4 presentations Bio-Labs(Pvt) Ltd
100 mg IV injection 1's 119143 PKR 3,000.682026-07-27 PKR 3,000.68/ vial/unit
150 mg IV injection 1's 119142 PKR 4,501.602026-07-27 PKR 4,501.60/ vial/unit
34 mg IV injection 1's 082407 PKR 1,199.812026-07-27 PKR 1,199.81/ vial/unit
68 mg IV injection 1's 116314 PKR 2,000.072026-07-27 PKR 2,000.07/ vial/unit
Colimate1 presentation MTI MEDICAL (PVT.) LTD
1 MIU Injection 1's 097779 PKR 1,199.812026-10-06 PKR 1,199.81/ vial/unit
Colimethate5 presentations TABROS PHARMA (PVT). LTD.
1 MIU Powder for solution for IV injection 1's 097181 PKR 1,199.812026-07-27 PKR 1,199.81/ vial/unit
2 MIU Powder for solution for IV injection/infusion 1's 107733 PKR 2,000.072026-07-27 PKR 2,000.07/ vial/unit
3 MIU (≈100 mg colistin base activity) Powder for injection/infusion 1's 108905 PKR 3,000.682026-07-27 PKR 3,000.68/ vial/unit
3 MIU (≈100 mg colistin base activity) Powder for solution for injection/infusion 10's 108905 PKR 28,806.972026-07-27 PKR 2,880.70/ vial/unit
4.5 MIU Powder for solution for injection 1's 120139 PKR 4,207.102026-07-27 PKR 4,207.10/ vial/unit
Colistim4 presentations Pharmasol (Pvt) Ltd.
3 MIU Injection 1's 124681 PKR 3,000.682026-07-24 PKR 3,000.68/ vial/unit
3 MIU Injection 10's 124681 PKR 28,806.972026-07-24 PKR 2,880.70/ vial/unit
4.5 MIU Injection 1's 124680 PKR 4,501.602026-07-24 PKR 4,501.60/ vial/unit
80 mg (≈34 mg colistin) Injection 1's 089922 PKR 3,106.342026-07-24 PKR 3,106.34/ vial/unit
Colistimethate Sodium2 presentations Mukhtar Enterprises
1 MIU Powder for solution for IV injection/infusion 1's 093937 PKR 1,199.812026-07-22 PKR 1,199.81/ vial/unit
2 MIU Powder for solution for IV injection/infusion 1's 094757 PKR 2,000.072026-07-22 PKR 2,000.07/ vial/unit
Colistizon3 presentations Horizon Healthcare (pvt.) ltd.
1 MIU (≈34 mg colistin base activity) Injection 1’s 116306 PKR 1,852.992026-07-27 PKR 1,852.99/ vial/unit
2 MIU (≈68 mg colistin base activity) Injection 1’s 116703 PKR 3,088.692026-07-27 PKR 3,088.69/ vial/unit
4.5 MIU (≈150 mg colistin base activity) Injection 1’s 116704 PKR 3,474.352026-07-27 PKR 3,474.35/ vial/unit
Colmat4 presentations Vision Pharmaceuticals Pvt Ltd
1 MIU Dry powder for injection 1's 108414 PKR 2,401.092026-07-27 PKR 2,401.09/ vial/unit
2 MIU Dry powder for injection 1's 119158 PKR 2,000.072026-07-27 PKR 2,000.07/ vial/unit
3 MIU Dry powder for injection 1's 119159 PKR 3,000.682026-07-27 PKR 3,000.68/ vial/unit
4.5 MIU (≈150 mg colistin base activity) Dry powder for injection 1's 119160 PKR 4,501.602026-07-27 PKR 4,501.60/ vial/unit
Colmixin2 presentations M/s. Genix Pharma (Pvt) Ltd.
1 MIU Powder for solution for IV injection 1's 107612 PKR 2,569.172026-07-23 PKR 2,569.17/ vial/unit
2 MIU Injection 1's 125292 PKR 2,000.072026-07-23 PKR 2,000.07/ vial/unit
Colybid1 presentation SAFE PHARMACEUTICAL (PVT) LTD
1 MIU Injection 1's 105370 PKR 2,401.542024-07-01 PKR 2,401.54/ vial/unit
Genthate3 presentations Biogen Life Sciences
1 MIU Injection 1's 108054 PKR 1,199.842026-08-17 PKR 1,199.84/ vial/unit
2 MIU Injection 1's 108055 PKR 2,000.122026-08-17 PKR 2,000.12/ vial/unit
4.5 MIU Injection 1's 121550 PKR 4,009.172025-07-01 PKR 4,009.17/ vial/unit
Klisty1 presentation The Searle Company Limited
1 MIU Injection 1's 120100 PKR 1,199.812026-07-23 PKR 1,199.81/ vial/unit
Komplet2 presentations Athan Pharmaceuticals
2 MIU Injection 1's 137121 PKR 1,727.002026-08-04 PKR 1,727.00/ vial/unit
4.5 MIU Injection 1's 137120 PKR 3,887.002026-08-04 PKR 3,887.00/ vial/unit
LISCOWIL1 presentation Wilshire Laboratories (Private) Limited
1 MIU Injection 1s 116450 PKR 2,223.582026-10-06 PKR 2,223.58/ vial/unit
Price movement

Official price changes for Colistimethate sodium

7 official price changes across 59 tracked presentations (records from 27 Nov 2023); median change +4.9%; largest +4.9% (Biothate 100 mg)

Each bar shows how many packs had an official DRAP price change in that month (amber: increase, teal: decrease). The figure above a bar is the median change. Hover or tap a bar for detail; the table below lists the largest changes.

BrandPackEffectiveOld to newChange
Biothate 100 mg1's20 Aug 2026PKR 2,859.51 to 3,000.77+4.9%
Colimate 1 MIU1's6 Oct 2026PKR 1,143.33 to 1,199.81+4.9%
Biothate 1 MIU1’s25 Sep 2026PKR 1,143.33 to 1,199.81+4.9%
Genthate 1 MIU1's17 Aug 2026PKR 1,143.36 to 1,199.84+4.9%
LISCOWIL 1 MIU1s6 Oct 2026PKR 2,118.91 to 2,223.58+4.9%
Genthate 2 MIU1's17 Aug 2026PKR 1,905.97 to 2,000.12+4.9%
Genthate 4.5 MIU1's1 Jul 2025PKR 3,887.00 to 4,009.17+3.1%
A to Z

All 25 Colistimethate sodium brands in Pakistan

  • Biothate Biogen Pharma · 1 MIU injection, 100 mg injection
  • CBA 150 Biocare Pharmaceutica · 150 mg injection
  • Choligene Genetics Pharmaceuticals Pvt. Ltd · 150 mg injection, 34 mg injection, 68 mg injection
  • Colaite English Pharmaceutical Industries · 1 MIU injection
  • Colemset Solaris Life Sciences Private Limited · 1 MIU (≈34 mg colistin base activity) injection, 2 MIU (≈68 mg colistin base activity) injection, 4.5 MIU injection
  • Colemset-3MIU Solaris Life Sciences Private Limited · 3 MIU (approx. 100 mg colistin base activity) injection
  • Coliate English Pharmaceutical Industries · 2 MIU (≈68 mg colistin base activity) injection, 4.5 MIU (≈150 mg colistin base activity) injection
  • Colicraft Bio-Labs(Pvt) Ltd · 100 mg injection, 150 mg injection, 34 mg injection, 68 mg injection
  • Colimate MTI MEDICAL (PVT.) LTD · 1 MIU injection
  • Colimethate TABROS PHARMA (PVT). LTD · 1 MIU injection, 2 MIU infusion, 3 MIU (≈100 mg colistin base activity) infusion, 4.5 MIU injection
  • Colistim Pharmasol (Pvt) Ltd · 3 MIU injection, 4.5 MIU injection, 80 mg (≈34 mg colistin) injection
  • Colistimethate Sodium Mukhtar Enterprises · 1 MIU infusion, 2 MIU infusion
  • Colistizon Horizon Healthcare (pvt.) ltd · 1 MIU (≈34 mg colistin base activity) injection, 2 MIU (≈68 mg colistin base activity) injection, 4.5 MIU (≈150 mg colistin base activity) injection
  • Colmat Vision Pharmaceuticals Pvt Ltd · 1 MIU injection, 2 MIU injection, 3 MIU injection, 4.5 MIU (≈150 mg colistin base activity) injection
  • Colmixin M/s. Genix Pharma (Pvt) Ltd · 1 MIU injection, 2 MIU injection
  • Colybid SAFE PHARMACEUTICAL (PVT) LTD · 1 MIU injection
  • Genthate Biogen Life Sciences · 1 MIU injection, 2 MIU injection, 4.5 MIU injection
  • Klisty The Searle Company Limited · 1 MIU injection
  • Komplet Athan Pharmaceuticals · 2 MIU injection, 4.5 MIU injection
  • LISCOWIL Wilshire Laboratories (Private) Limited · 1 MIU injection
  • Listono Horizon Healthcare (pvt.) ltd · 1 MIU injection, 2 MIU injection, 3 MIU injection, 4.5 MIU injection
  • Mellistin Macter International Limited · 1 MIU injection
  • Nogotex Nabiqasim Industries (Pvt) Ltd · 1 MIU injection, 2 MIU injection, 3 MIU injection, 4.5 MIU (≈150 mg colistin base activity) injection
  • OLMETHATE SAMI Pharmaceuticals Pvt. Ltd · 1 MIU injection, 150 mg injection, 2 MIU injection
  • Stacolmi STALLION PHARMACEUTICALS PVT LTD · 1 MIU injection
Questions

Colistimethate sodium in Pakistan: common questions

How many Colistimethate sodium brands are available in Pakistan?

25 brands of Colistimethate sodium are registered in Pakistan, made or imported by 22 companies.

What is the price of Colistimethate sodium 1 MIU injection in Pakistan?

The lowest official price is PKR 1,109 per vial (OLMETHATE by SAMI Pharmaceuticals Pvt. Ltd), the middle (median) price is PKR 1,200 per vial and the highest is PKR 3,617 per vial (Mellistin). These prices are for 15 brands with an official price. The cheapest pack is OLMETHATE 1's at PKR 1,109.

What is the price of Colistimethate sodium 2 MIU injection in Pakistan?

The lowest official price is PKR 1,727 per vial (Komplet by Athan Pharmaceuticals), the middle (median) price is PKR 2,000 per vial and the highest is PKR 2,000 per vial (Genthate). These prices are for 7 brands with an official price. The cheapest pack is Komplet 1's at PKR 1,727.

What is the price of Colistimethate sodium 4.5 MIU injection in Pakistan?

The lowest official price is PKR 3,887 per vial (Komplet by Athan Pharmaceuticals), the middle (median) price is PKR 4,354 per vial and the highest is PKR 4,502 per vial (Listono). These prices are for 6 brands with an official price. The cheapest pack is Komplet 1's at PKR 3,887.

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Cite this record

Molecule record · ATC J01
MedInfoBase. (2026). Colistimethate sodium — registered brands and price distribution in Pakistan [Data set]. MedInfoBase. Retrieved November 10, 2026, from https://medinfobase.com/generic/colistimethate-sodium/ ATC J01.
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