USP L32 column: Chiral ligand exchange (L-proline copper)
Chiral ligand-exchange phase: L-proline copper complex bonded to irregular silica of 5-10 um.
Mode: chiral Typical pH range: about 2-7.5 (copper-containing aqueous eluent)
Typical uses
- Enantiomers of amino acids and hydroxy acids
- Chiral impurity of amino-acid drugs
Common sizes (length x internal diameter, particle size)
- 250 x 4.6 mm, 5 um
- 150 x 4.6 mm, 3 um
Tender wording (brand-neutral)
HPLC column with USP L32 packing (Chiral ligand exchange (L-proline copper)), 250 x 4.6 mm, 5 um (length x internal diameter, particle size); stainless-steel or equivalent hardware with standard fittings; recommended pH and temperature range to be stated by the bidder; each column supplied with its certificate of analysis and test chromatogram, batch/lot number and serial number; shelf life not less than 2 years from delivery; any make meeting the USP L32 designation and the stated dimensions is acceptable.
Size:
Changing length or particle size
You can keep the USP L32 packing and use a different length, particle size or diameter within the harmonized USP 621 limits. Check your columns with the calculator.
Related column types
L40 Cellulose tris(3,5-dimethylphenylcarbamate), coated | L41 Alpha1-acid glycoprotein (AGP) chiral | L45 Beta-cyclodextrin (hydroxypropyl) chiral | L51 Amylose tris(3,5-dimethylphenylcarbamate), coated | L66 Crown ether chiral, (S)-18-crown-6
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