USP L41 column: Alpha1-acid glycoprotein (AGP) chiral
Alpha1-acid glycoprotein immobilized on 5 um spherical silica.
Mode: chiral Typical pH range: about 3-7.5 (protein phase; avoid extremes)
Typical uses
- Enantiomers of basic and neutral drugs in aqueous mobile phase
- Chiral impurity tests in reversed-phase mode
Common sizes (length x internal diameter, particle size)
- 150 x 4.0 mm, 5 um
- 100 x 4.0 mm, 5 um
Protein column: low organic content, moderate temperature, limited loading.
Tender wording (brand-neutral)
HPLC column with USP L41 packing (Alpha1-acid glycoprotein (AGP) chiral), 150 x 4.0 mm, 5 um (length x internal diameter, particle size); stainless-steel or equivalent hardware with standard fittings; recommended pH and temperature range to be stated by the bidder; each column supplied with its certificate of analysis and test chromatogram, batch/lot number and serial number; shelf life not less than 2 years from delivery; any make meeting the USP L41 designation and the stated dimensions is acceptable.
Size:
Changing length or particle size
You can keep the USP L41 packing and use a different length, particle size or diameter within the harmonized USP 621 limits. Check your columns with the calculator.
Related column types
L32 Chiral ligand exchange (L-proline copper) | L40 Cellulose tris(3,5-dimethylphenylcarbamate), coated | L45 Beta-cyclodextrin (hydroxypropyl) chiral | L51 Amylose tris(3,5-dimethylphenylcarbamate), coated | L66 Crown ether chiral, (S)-18-crown-6
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