USP L50 column: Mixed-mode resin: RP + strong anion exchange
Multifunction resin combining reversed-phase retention with strong anion-exchange sites (EVB-DVB core with latex coating); 3-15 um.
Mode: mixed-mode Typical pH range: 0-14 for most polymer IC resins (check eluent limits)
Typical uses
- Anions alongside hydrophobic analytes
- IC with organic solvents
Common sizes (length x internal diameter, particle size)
- 250 x 4 mm (analytical)
- 250 x 2 mm (microbore)
- 50 x 4 mm guard
Tender wording (brand-neutral)
HPLC column with USP L50 packing (Mixed-mode resin: RP + strong anion exchange), 250 x 4 mm (analytical) (length x internal diameter, particle size); stainless-steel or equivalent hardware with standard fittings; recommended pH and temperature range to be stated by the bidder; each column supplied with its certificate of analysis and test chromatogram, batch/lot number and serial number; shelf life not less than 2 years from delivery; any make meeting the USP L50 designation and the stated dimensions is acceptable.
Size:
Changing length or particle size
You can keep the USP L50 packing and use a different length, particle size or diameter within the harmonized USP 621 limits. Check your columns with the calculator.
Related column types
L78 Mixed-mode silica: RP (>C8) + anion exchange | L85 Mixed-mode silica: RP (>C8) + weak cation exchange
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