USP L38 column: Methacrylate SEC, water-soluble samples

Methacrylate-based size-exclusion packing for water-soluble samples.

Mode: size-exclusion   Typical pH range: wide, roughly 1-13 (polymer base)

Typical uses

  • Water-soluble polymers and excipients
  • Molecular weight distribution

Common sizes (length x internal diameter, particle size)

  • 300 x 7.8 mm, 5-8 um
  • 300 x 7.5 mm, 10-13 um

Tender wording (brand-neutral)

HPLC column with USP L38 packing (Methacrylate SEC, water-soluble samples), 300 x 7.8 mm, 5-8 um (length x internal diameter, particle size); stainless-steel or equivalent hardware with standard fittings; recommended pH and temperature range to be stated by the bidder; each column supplied with its certificate of analysis and test chromatogram, batch/lot number and serial number; shelf life not less than 2 years from delivery; any make meeting the USP L38 designation and the stated dimensions is acceptable.

Size:

Changing length or particle size

You can keep the USP L38 packing and use a different length, particle size or diameter within the harmonized USP 621 limits. Check your columns with the calculator.

Related column types

L25 Polymethacrylate SEC, water-soluble polymers (MW ~100-5000) | L33 SEC silica for dextrans (4-500 kDa) | L39 Hydrophilic polyhydroxymethacrylate gel (SEC) | L59 Protein SEC on coated silica/hybrid (5-7000 kDa)

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