USP L52 column: SCX silica (sulfopropyl / sulfoethyl)
Strong cation-exchange packing with sulfopropyl or sulfoethyl groups on porous silica of 1-10 um.
Mode: ion-exchange Typical pH range: about 2-7.5
Typical uses
- Cation exchange of basic drugs, peptides and proteins
- Charge-variant type separations
Common sizes (length x internal diameter, particle size)
- 250 x 4.6 mm, 5 um
- 150 x 4.6 mm, 5 um
Tender wording (brand-neutral)
HPLC column with USP L52 packing (SCX silica (sulfopropyl / sulfoethyl)), 250 x 4.6 mm, 5 um (length x internal diameter, particle size); stainless-steel or equivalent hardware with standard fittings; recommended pH and temperature range to be stated by the bidder; each column supplied with its certificate of analysis and test chromatogram, batch/lot number and serial number; shelf life not less than 2 years from delivery; any make meeting the USP L52 designation and the stated dimensions is acceptable.
Size:
Changing length or particle size
You can keep the USP L52 packing and use a different length, particle size or diameter within the harmonized USP 621 limits. Check your columns with the calculator.
Related column types
L9 SCX on silica | L14 SAX on silica | L17 SCX resin, H+ form (organic acid / ion-exclusion) | L19 SCX resin, Ca2+ form (sugars) | L22 Cation-exchange polystyrene gel (sulfonic) | L23 SAX polymethacrylate/polyacrylate gel | L34 SCX resin, Pb2+ form (sugar alcohols) | L46 SAX, latex-agglomerated PS-DVB (9-11 um) | L53 WCX resin, carboxylic/phosphonic grafted EVB-DVB (cations IC) | L58 SCX resin, Na+ form (sugars/oligosaccharides)
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